Digital life world model ecosystem
Every change in life, predicted in silico
PERTURBMIND is building PerturbSeek, a digital life world model ecosystem that simulates, in silico, how life responds to every perturbation.
01Challenge01 / The challenge
Life faces far more perturbations than experiments cover
Genes, drugs, doses, cell types, tissues and organisms combine into an almost endless space, and experiments reach only a small part of it. A model that works only on known systems falls far short; the real challenge is to learn laws that generalize to the unknown.
02 / Our approach
Our method
Drag the point and watch it flow to a new state.
- 01
See cells and organisms whole
Not a handful of highly variable genes: we start from every protein-coding gene and extend to more modalities, building a complete digital life state space.
- 02
Treat perturbation as flow
We model each perturbation as a flow field that drives how the states of living systems evolve.
- 03
Learn general dynamic laws
Our aim is to learn general dynamic laws that transfer to entirely new cellular and biological contexts, not to memorize existing experimental results.
03 / What we are building
PerturbSeek Ecosystem
Traditional AIDD centers on targets, fitting keys to known locks. We choose to simulate how the state of the whole living system changes, and to identify effective interventions under specific disease and clinical constraints.
04Applications
- Disease mechanism analysis
- Novel target discovery
- New-modality drug development
PerturbSeek
02Engine
- Build world models
- Simulate state changes
- Identify interventions
01Foundations
- Perturbation omics
- Geometric deep learning
- World model theory
04 / Who we are
Across diverse disciplines, understanding life
People from these fields refine one model, as one team.
- 01Computational biology
- 02Machine learning
- 03Single-cell science
- 04Drug discovery
- 05Product engineering
Our team’s earlier work appeared in Nature Methods, Nature Machine Intelligence, Cancer Cell and other journals; since the lab stage, we have worked closely with leading pharma and CROs in China and abroad.
Meet the team05 / Updates
Latest progress
06 / Get in touch
Let’s predict life’s next change together
Whether you’re in pharma, healthcare, academia or investment, we’d love to hear from you.